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Deflazacort

Brand(s): Defnalone

Manufacturer: Lupin

Emflaza is a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients at the age of 5 and older.
PackagePer tabletPriceOrder
6mg × 30 tablet$ 2.17$ 64.95Buy Now!
6mg × 60 tablet$ 1.32$ 78.95Buy Now!
6mg × 90 tablet$ 1.05$ 94.95Buy Now!
6mg × 120 tablet$ 0.87$ 103.95Buy Now!
PackagePer tabletPriceOrder
24mg × 24 tablet$ 5.79$ 138.95Buy Now!
24mg × 36 tablet$ 5.50$ 197.95Buy Now!
24mg × 60 tablet$ 5.17$ 309.95Buy Now!
24mg × 90 tablet$ 5.02$ 451.95Buy Now!
PackagePer tabletPriceOrder
30mg × 24 tablet$ 7.00$ 167.95Buy Now!
30mg × 36 tablet$ 6.72$ 241.95Buy Now!
30mg × 60 tablet$ 6.25$ 374.95Buy Now!

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

  • Hypersensitivity to deflazacort;
  • Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
  • Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
  • Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
  • Gastrointestinal Perforation: GI disorders;
  • Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
  • Effects on Bones: decreases in bone mineral density;
  • Serious Skin Rashes;
  • Ophthalmic Effects: May include cataracts, infections, and glaucoma;
  • Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

  • Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
  • Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.

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